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A Comparative Study of Efficacy of once Daily 0.1% Tazarotene and Adapalene Gel for the Treatment of Facial Acne Vulgaris
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Mukunda Ranga Swaroop
Objectives: To compare the efficacy of once daily topical 0.1% Tazarotene and Adapalene gel in the treatment of mild to moderate facial acne vulgaris.
Method: A total number of 60 patients with mild to moderate facial acne vulgaris attending out-patient department of Dermatology, Venereology and Leprosy from Oct.2004 – April. 2006 were studied. Patients were allocated alternately to group A and group B. Group A received 0.1% Tazarotene gel and group B patients received 0.1% Adapalene gel and were advised to apply topically once daily in the evening. Patients were followed up on 4th, 8th and 12th week.
Results: At the 4thweek of post treatment evaluation, the non-inflammatory lesions (comedones) responded early to Tazarotene 0.1% gel than to Adapalene 0.1% gel. At the end of 12th week treatment period, Tazarotene 0.1% gel had an overall superiority to Adapalene 0.1% gel as an antiacne agent.
Conclusion: The results of the study show that Tazarotene 0.1% gel is a better anticomedogenic agent with rapid rate of clinical improvement when compared with Adapalene 0.1% gel.
Key Words: Acne vulgaris; Tazarotene 0.1% gel; Adapalene 0.1% gel, once daily, Mild to moderate acne
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How to Cite This Article
Vancouver
Swaroop MR. A Comparative Study of Efficacy of once Daily 0.1% Tazarotene and Adapalene Gel for the Treatment of Facial Acne Vulgaris [Internet]. IP Indian J Clin Exp Dermatol. 2015 [cited 2025 Oct 01];1(1):4-8. Available from: https://doi.org/
APA
Swaroop, M. R. (2015). A Comparative Study of Efficacy of once Daily 0.1% Tazarotene and Adapalene Gel for the Treatment of Facial Acne Vulgaris. IP Indian J Clin Exp Dermatol, 1(1), 4-8. https://doi.org/
MLA
Swaroop, Mukunda Ranga. "A Comparative Study of Efficacy of once Daily 0.1% Tazarotene and Adapalene Gel for the Treatment of Facial Acne Vulgaris." IP Indian J Clin Exp Dermatol, vol. 1, no. 1, 2015, pp. 4-8. https://doi.org/
Chicago
Swaroop, M. R.. "A Comparative Study of Efficacy of once Daily 0.1% Tazarotene and Adapalene Gel for the Treatment of Facial Acne Vulgaris." IP Indian J Clin Exp Dermatol 1, no. 1 (2015): 4-8. https://doi.org/