Histopathological study of cutaneous non-neoplastic lesions in punch biopsies

Original Article

Author Details : Sakthidasan Chinnathambi P*, Anitha Burra

Volume : 7, Issue : 2, Year : 2021

Article Page : 130-135


Suggest article by email


Background: Skin being the largest organ of the body, is subjected to constant environmental insults through direct and indirect targets. Non-neoplastic lesions of skin comprise a vast array of diseases, which are usually approached by pattern based method in histopathology for microscopic diagnosis. This study was undertaken with an intention to learn such diseases by a simple minimally invasive punch biopsy procedure.
Materials and Methods: A 2 year retro-prospective study of 82 punch biopsies which were documented as non-neoplastic lesions of skin were studied with respect to their demographical and histopathological profile. Simple descriptive statistics was applied in Microsoft Excel software.
Results: Out of the 82 cases studied, 46(56%) were males and 36(44%) were females. Maximum number of cases (n=23) were seen in 21-30 years of age. Most prominent site of lesions biopsied were from lower limb (23 cases) with legs being the commonest among them. Cutaneous infections (n=25) was the most common clinical category, with Mycobacterial lesions as the prominent subcategory (n=16). Granulomatous reaction constituted the most common major tissue reaction pattern among other patterns with a total number of 17 cases out of 82. Panniculitis was the most common minor reaction pattern observed.
Conclusion: The pattern based approach in routine histopathological analysis proves a valuable descriptive tool for reaching an accurate diagnosis in cutaneous non-neoplastic lesions.

Keywords: Biopsy, Nonneoplastic lesions, Skin.

How to cite : Sakthidasan Chinnathambi P, Burra A , Histopathological study of cutaneous non-neoplastic lesions in punch biopsies. IP Indian J Clin Exp Dermatol 2021;7(2):130-135

Copyright © 2021 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)

Article History

Received : 23-04-2021

Accepted : 06-05-2021

Available online : 26-05-2021

View Article

PDF File   Full Text Article


PDF File   XML File   ePub File

Digital Object Identifier (DOI)

Article DOI


Article Metrics

Article Access statistics

Viewed: 103

PDF Downloaded: 74