Subcutaneous fat necrosis of newborn - A rare case report of lobular panniculitis in a neonate

Case Report

Author Details : Samagani Akshay*, Pemmanda Raju Belliappa, Raveendra Leena

Volume : 7, Issue : 3, Year : 2021

Article Page : 266-269

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Subcutaneous fat necrosis of newborn is a rare cutaneous disorder affecting neonates. It usually presents as subcutaneous nodules or plaques, within the first few weeks of life, following an eventful delivery. It is characterized by hypercalcemia, which may present with lethargy, irritability, hypotonia and dehydration, mimicking sepsis. Histopathology is proven to be the gold standard in diagnosis with characteristic lobular panniculitis, mixed inflammatory cell infiltrate and radially arranged crystals. This needs to be differentiated from other causes of lobular panniculitis, as early diagnosis and treatment to prevent long-term complications are advocated. Education of parents regarding the disease and danger signs of hypercalcemia and weekly monitoring of serum calcium is recommended. Treatment based on rehydration, dietary vitamin D and calcium restriction, Furosemide and prednisolone are considered.We have discussed a case of subcutaneous fat necrosis, in an 8-week-old male baby.
Key Messages: Subcutaneous fat necrosis is an important differential in neonates presenting with palpable subcutaneous nodules, along with sclerema neonatorum. Severe complications like hypercalcemia should be detected early and managed aggressively to prevent morbidities and mortalities associated with it. Symptomatic management, use of calcium lowering drugs and regular monitoring of calcium levels are recommended.

Keywords: subcutaneous fat necrosis of newborn, perinatal asphyxia, hypercalcemia, lobular panniculitis, neonatal sepsis

How to cite : Akshay S, Belliappa P R, Leena R, Subcutaneous fat necrosis of newborn - A rare case report of lobular panniculitis in a neonate. IP Indian J Clin Exp Dermatol 2021;7(3):266-269

Copyright © 2021 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

Article History

Received : 07-06-2021

Accepted : 26-07-2021

Available online : 06-09-2021

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