A study of efficacy of platelet rich plasma in treatment of androgenetic alopecia in male patients

• Author Details:   
• Krishnendra Varma
• Ankit Agrawal
• Meetesh Agrawal

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Background: Androgenetic alopecia is a very common clinical condition encountered by the dermatologists in their daily practice.
Aims: To study the efficacy of platelet rich plasma in treatment of androgenetic alopecia in male patients.
Settings and design: Observational and interventional study.
Methods: A total of 30 cases of clinically diagnosed male patients with androgenetic alopecia in the age group of 15-50 years constituted the subject material for present study. Detailed history and clinical examination of cases was done. All the routine investigations were carried out.
Statistical analysis used: Data analysis was done by using statistical package for social sciences (SPSS) and “paired t test”.
Results: A total of 30 patients were studied. Large number belonged to the age group 26-30(36.7%) years and 21-25 years(33.3) respectively. Majority are from class 2 to 5, Hamilton Norwood classification of AGA. The family history was positive in 19 cases (63.3%). Frontal, parietal and occipital areas were involved in maximum number of patients i.e. in 20 patients (66.7%). The patients reported clinical improvement in the form of hair count, hair thickness, hair density with statistically significant p-value (p-0.00) after an average of 2-3 sessions.
Conclusion: In our study of 30 patients, 20 patients showed improvement of varying degrees ranging from +1 to +7 according to Jaeschke scale with significant p-value (p-0.00) after treatment with platelet rich plasma(PRP) based upon which we conclude that platelet rich plasma(PRP) is efficacious in the treatment of androgenetic alopecia.

Key-words: Androgenetic alopecia(AGA), Platelet rich plasma(PRP), Males